From the Stage 2 SACE Biology course outline, this video discusses:
- The phenotypic expression of genes depends on factors controlling transcription and translation. These include the products of other genes and the environment.
- Cellular differentiation associated with tissue growth and development is controlled by gene expression.
• Recognise that changes in DNA methylation and histone modification can alter gene expression.
- Epigenetic changes can lead to phenotypic differences between identical siblings, phenotypic differences between clones, and may cause human diseases.
• Explain how epigenetic modifications in genes that control cell division, such as changes in DNA methylation, can lead to cancer.
