Oxford Nanopore technology uniquely delivers high outputs of any-length reads that span full-length RNA transcripts, facilitating their accurate, unambiguous analysis and resulting in complete transcriptome characterisation at the isoform level.
Nanopore RNA and cDNA sequencing generates novel insights into differential isoform expression and allele-specific expression, even at single-cell resolution — in one go. Furthermore, with direct RNA sequencing that does not require reverse transcription or amplification, it is possible to detect base modifications (such as methylation) in native RNA transcripts. The scalability of Oxford Nanopore sequencing devices means that researchers do not need to batch a high number of samples, reducing waiting times and generating faster results.
Learn more: https://nanoporetech.com/applications/techniques/rna-and-cdna-sequencing
