Distance between two DNA Sequences using Phylip Package

In this video, we describe computing four different distances between nucleic acid sequences uing DNADIST program of the Phylip package. The distances are the Jukes-Cantor formula, one based on Kimura's 2- parameter method, the F84 model used in DNAML, and the LogDet distance. The distances can also be corrected for gamma-distributed and gamma-plus-invariant-sites-distributed rates of change in different sites. Rates of evolution can vary among sites either in a prespecified way, or according to a Hidden Markov model. Music Source: Royalty free music “Straight Weather” available in YouTube is used in this video.