How do we use linkage to find the alleles that cause genetic disease? How do we develop a genetic hypothesis about the linkage between a polymorphism and the allele that causes a genetic disease? How do we use the binomial distribution to test that hypothesis? What is a likelihood ratio? What is a lod score?
This video lecture was recorded at the University of Wisconsin -- Stout in the fall of 2021. It accompanies my BIO 332 Genetics course, which was taught with Hartl's "Genetics: Analysis of Genes and Genomes."