Impurity Profiling and Structure Elucidation via ACD/Labs

Kristof Cank (Sutro Biopharma) shares his experience using ACD/Labs software to elucidate and verify structures of small molecules and linker-warhead parts of antibody drug conjugates (ADCs) and to identify, isolate, and characterize impurities. He presents various workflows to demonstrate the utility and convenience of a single software interface that enables: • NMR, LC, and MS data processing • 1H, 13C NMR predictions • Dereplication of known structures • Automated structure verification (ASV) • Report creation and database building