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Machine Learning in Biotech: Alphafold

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Apr 21, 2025
45:46

Here I discuss ML, ML applications in Biotech, and the original alpha fold paper: https://www.nature.com/articles/s41586-021-03819-2 Timestamps: 0:00 Introduction and Qualifications 1:50 Multi-Dimensional Space 3:30 Inputs to Machine Learning 3:40 Data Arrays 4:30 Classification Tasks Examples 5:00 No Free Lunch Theorem 5:40 Many Different Kinds of Machine Learning 6:00 Linear Algebra 7:45 Training Sets and Test Sets 10:45 Truth Table 14:25 Linear Regression 15:20 Logistic Regression 16:00 Decision Trees 17:00 Random Forrest 17:50 Support Vector Machines 18:30 Neural Networks 20:00 Limitations of ML 24:20 Alpha Fold 26:00 .PDB files 27:00 Figure 1. 28:00 Comparing Protein Resolutions 30:15 Software Model of Alpha Fold 32:00 Multi Sequence Alignment 33:00 Pairing Matrix 36:00 Evoformer 40:00 Laymen Terms 41:00 Criticisms 44:20 Theme Song

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