In this introductory webinar, the Secoya Crystallization Technology is demonstrated. This technology focuses on the use of millifluidic capillary reactors that enable the most profound control on all crystallization parameters, making spontaneous nucleation controllable and exploitable. Several examples using organic molecules like active pharmaceutical ingredients are shown, also pinpointing to the way the nucleation can be controlled to crystallize the polymorphic form of choice and at the same time steer the process towards the final desired material attributes, especially size. As such, the complex multi-step process of crystallization (seed preparation, crystal growth, isolation, milling, etc.) is reduced to a simple setup where the nucleation, growth and isolation of organic or inorganic compounds are fully coupled from the (heated) solution to a crystalline material.
