mRNA Splicing - mRNA post-transcriptional processing/modifications - What is alternative splicing?
References/Resources: https://www.patreon.com/the_Crux pre-mRNA splicing process and mechanism deep-dive video. What are the different types of introns? How does Spliceosome assemble? What are U2-type and U12-type introns? How are U2-type introns removed? How does spliceosome remove introns? What is an outron? What is canonical splicing, alternative splicing, trans splicing, and back splicing? Jump to your favorite section: 00:00 Outline 00:24 What starts the splicing process? 02:45 Different types of introns 04:30 snRNPs 06:25 Spliceosome assembly 12:44 Trans-esterification steps 13:55 Why is splicing done? 16:16 Outron 18:17 Back splicing Other RNA processing and modifications: 3' RNA tailing deep-dive video: https://youtu.be/104uFOtDZP0 5' RNA capping deep-dive video: https://youtu.be/_tPT1zxLdKI Eukaryotic RNA processing - Overview: https://youtu.be/UteY3Iah88Q ***Complete Transcription Playlist*** Advanced concepts in Transcription: https://www.youtube.com/playlist?list=PL0Ymnd-zt4Ij2VcAOHNUweftSElVsc-MX Related videos - Eukaryotic Transcription - Termination: https://youtu.be/fxvuUHvixbI Eukaryotic Transcription - Elongation: https://youtu.be/g-_nvnN32J8 Eukaryotic Transcription - Initiation: https://youtu.be/s5b87Z7MWCM Eukaryotic Transcription - The histone problem: https://youtu.be/KygzEjYfUts Eukaryotic Transcription - Introduction: https://youtu.be/QmTf4M4qrbI Eukaryotic Promoter Video: https://youtu.be/tZEWEQib_F8 Prokaryotic Transcription Initiation: https://youtu.be/JebsvaBCpQo Prokaryotic Transcription Elongation (BROWNIAN MOTION MODEL): https://youtu.be/7kfqeIjIzMY ***Playlists that you must explore*** Advanced concepts in Genetics: https://www.youtube.com/playlist?list=PL0Ymnd-zt4IgEBW8xWPZhHSN4O8HXqQ6j Journal Club: https://www.youtube.com/playlist?list=PL0Ymnd-zt4IiRbmmqRbJdTskp4e5AhgrQ Thanks for watching :) Hit that LIKE button if you want more knowledge! COMMENT your questions, suggestions, and thoughts :) And I hope you have SUBSCRIBED because there is a lot more coming! :D
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