Faster and cheaper sequencing technologies have radically changed the way we study biological systems. They let us assemble the genomes of poorly studied species, reveal the expression of thousands of genes simultaneously, and address many fundamental biological questions, often in real time. In this three part series, we describe these new sequencing technologies, explore what we can do with them, and consider the myriad ways in which this wealth of data is now being used.
In this first of three presentations, we will explore first generation (Sanger), second generation (Illumina) and third generation (PacBio) sequencing technologies.
This series was initially developed for the third-year course in genome analysis at Massey University in New Zealand. The presenter, Murray Cox, is Professor of Computational Biology at Massey University (https://www.massey.ac.nz) and leads the Computational Biology Research Group (https://www.genomicus.com).