Part II Dry Granulation Formulation & Tableting Techniques

A comparative study was performed using 3 levels of Acetaminophen active in a tablet formulation. Powder flow, compactability and scalability was evaluated utilizing Natoli’s compaction emulator, Natoli's NP-RD30 rotary tablet press with Natoli AIM™ data acquisition software, and Alexanderwerk’s dry granulation roller compaction technology. Session II focuses on the dry granulation process and subsequent tableting.