Pharmacophore-Guided Docking

This video covers MOE applications for protein-ligand docking, including pharmacophore-guided docking which ensures high-quality docked poses with all key interactions preserved. 0:31 Loading a PDB Complex 0:51 Structure preparation with QuickPrep 2:42 Rendering using the System Manager 3:14 Protein-Ligand interaction analysis 4:06 Binding pocket analysis using Surfaces 5:00 Setting up the unified Dock panel 8:18 Encoding key interactions using the Pharmacophore Editor 13:21 Running the docker 15:33 Quantitative analysis using the Database Viewer 16:50 Qualitative analysis using the Database Browser 17:58 Selecting best-docked poses for future reference __________________________________________________________________________________________________ Subscribe to our YouTube channel for updates: https://bit.ly/3ICXK0W Visit CCG at https://www.chemcomp.com/ Listen to our podcast: https://bit.ly/3WQGPKY Follow us on LinkedIn: https://www.linkedin.com/company/chemical-computing-group/ X: https://twitter.com/CCG_MOE/