Pleiotropy

Pleiotropy explained — fast. In this AP Biology video, you’ll learn how one gene can influence multiple traits by exploring two real-world examples you need to know for AP Bio: sickle-cell disease and cystic fibrosis. This video aligns with the 2025 AP Biology CED (Unit 5: Heredity — Pleiotropy). ✨ What you’ll learn • What pleiotropy means and why it matters in genetics • How sickle cell disease has pleiotropic effect, causing damage and pain, but also giving heterozygous carriers of sickle-cell gain malaria resistance • How a mutation in the CFTR gene leads to cystic fibrosis • How the mutation in CFTR causes multiple symptoms across body systems ✅ YouTube Chapters 0:00 — Introduction: What Is Pleiotropy? 0:25 — Pleiotropy in Sickle Cell Disease 3:42 — Pleiotropy in Cystic Fibrosis 📘 Free AP Bio Checklist Download the study checklist that tells you exactly what to review for every unit: ➡️ https://apbiosuccess.com/checklist 🚀 Master AP Bio the smart way Interactive tutorials • Flashcards • Quizzes • AI-powered FRQs with feedback ➡️ https://learn-biology.com 🎨 Credits Some images in this video were made with BioRender: https://www.biorender.com #heredity #genetics #pleiotropy