PolyPhen-2 Tutorial Series: Introduction

This introductory video to Polymorphism Phenotyping v2 (PolyPhen-2) provides a brief description of the tool and its home page. Want to practice applying this information? Check out the activities in our Sequence Comparison & Identity module on our website: https://www.jax.org/education-and-learning/high-school-students-and-undergraduates/teaching-the-genome-generation/stem-learning-resources?eduTopic=dff8d5d3-7b45-4af1-b0df-504053d7eef6 Or on LabXchange: https://www.labxchange.org/library/pathway/lx-pathway:430d9cc3-22f1-426c-885f-82119f469e64 PolyPhen-2: http://genetics.bwh.harvard.edu/pph2/ PolyPhen-2 Tutorial Series Playlist: https://www.youtube.com/playlist?list=PLWNp6Z5dXDZ61kvBXYlr60B6deiAVy-tj Genomic Education at The Jackson Laboratory: https://www.jax.org/education-and-learning Genetics Learning Resources from The Jackson Laboratory: https://www.jax.org/stem-resources Key moments: 0:00 Introduction 0:13 What is PolyPhen-2? 1:05 Orientation to the homepage 1:27 Applications of PolyPhen-2 2:11 Conclusion Keywords: PolyPhen-2, variant effect prediction