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Quality Control in CAR-T Therapy Development

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Apr 18, 2025
2:12

CAR-T therapy is transforming how we treat certain blood cancers. But ensuring quality and safety at every step of the workflow—from plasmid design to final product verification—is critical. In this animated explainer, you’ll see how the Spectrum Compact CE System offers a compact, flexible solution for two key analytical techniques: Sanger sequencing and fragment analysis. Together, these capabilities support rigorous quality control during the development of CAR-T therapies. In this video, you’ll learn how to: - Confirm plasmid design accuracy using Sanger sequencing - Verify CAR expression in modified T cells before infusion - Authenticate donor identity with fragment analysis to reduce the risk of sample mix-ups - Integrate a cost-effective, benchtop system into your gene and cell therapy workflows Built for scientists, the Spectrum Compact is designed to be simple to use without compromising performance. With dual functionality in one small footprint, it offers the data confidence you need—when and where you need it. 👇 Want to know more? Explore how Promega tools can help simplify your workflows while supporting the consistency and quality your work demands. Learn more about Spectrum Compact CE System: https://bit.ly/42GjgrH #CARTTherapy #CellAndGeneTherapy #SpectrumCompact #SangerSequencing #FragmentAnalysis #PlasmidQC #BiotechTools #Immunotherapy #GeneTherapy #LaboratoryInstrumentation

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Quality Control in CAR-T Therapy Development | NatokHD