Rat Fundus Strip Isolation

Rat Fundus Strip Isolation To record the dose response curve and to determine the pD2 value for Serotonin on Rat stomach (fundus part) strip. To record the dose response curve for Serotonin on isolated Rat stomach (fundus part) strip. To determine the pD2 value for Serotonin on Rat stomach (fundus part) strip In this video, we demonstrate how to record the Dose Response Curve (DRC) and determine the pD₂ value of Serotonin using an isolated rat stomach (fundus) strip preparation. This experiment is an important part of experimental pharmacology and helps in understanding receptor pharmacodynamics and drug potency. dose response curve, DRC experiment, pD2 value calculation, serotonin on rat fundus, rat stomach fundus strip, isolated tissue experiment, experimental pharmacology, serotonin pharmacology practical, log dose response curve, 5 HT experiment, agonist potency determination, organ bath experiment, pharmacology lab practical, receptor pharmacodynamics, pharmacy practical experiment The rat fundus is highly sensitive to Serotonin (5-HT), making it a suitable tissue for studying agonist activity. In this practical, we explain tissue preparation, mounting in organ bath, recording graded responses, plotting the log dose-response curve, and calculating the pD₂ value. The pD₂ value represents the negative logarithm of the molar concentration of the drug that produces 50% of the maximum response, indicating the potency of Serotonin. #DoseResponseCurve #pD2Value #Serotonin #RatFundus #ExperimentalPharmacology #PharmacologyPractical #5HT #OrganBathExperiment #BPharm #MPharm This video is highly useful for B.Pharm and M.Pharm students for pharmacology practical exams, viva preparation, and competitive exam revision. Watch till the end for a clear explanation of DRC plotting and pD₂ calculation. Dose Response Curve and pD₂ Value of Serotonin on Rat Fundus – Complete Practical How to Calculate pD₂ Value? | Serotonin on Rat Stomach Fundus DRC of Serotonin Explained | Experimental Pharmacology Practical Determination of pD₂ Value Using Rat Fundus Strip (Step-by-Step) Serotonin Dose Response Curve on Rat Fundus | Pharmacology Lab Experiment Please click the links for the In-vivo study protocols: https://www.researchsop.com/2022/04/List-of-All-SOPs-and-Documents-for-In-vivo-Laboratory.html