Tebbe reagent is a titanium–aluminium metallacycle. It is prepared from titanocene dichloride and trimethylaluminium in toluene. In a major application, a variety of carbonyl compounds like aldehyde, ketone, ester, lactone, thioester, amide, lactam and carbonate by the reaction with Tebbe reagent in the absence or presence of catalytic amount of base like pyridine or DMAP are transformed to the product with terminal alkene. In another application, acyl chloride, anhydride and imide are converted to enolate, sulfoxide to sulphide, selenoxide to selane and pyridine N-oxide to 2-methylpyridine.
