Watch Patrick Dempsey React to His First ET Interview!

ET was with the dad of three while being honored with the Impact Award presented by the American Cancer Society. More from Entertainment Tonight: https://www.youtube.com/channel/UCdtXPiqI2cLorKaPrfpKc4g?sub_confirmation=1 Exclusives from #ETonline : https://www.youtube.com/playlist?list=PLQwITQ__CeH2Y_7g2xeiNDa0vQsROQQgv