The hypothalamus, anterior pituitary and testes are interrelated in testicular functions. FSH from the pituitary stimulates spermatogenesis in the presence of testosterone. High concentration of testosterone is maintained due to the presence of androgen binding protein which is secreted by the sertoli cells. These cells also secrete another hormone called inhibit in which inhibits the action
of testosterone.
Testosterone secretion by Leydig cells is stimulated by LH. The testosterone has its action on different target cells. It diffuses into the seminiferous tubules and stimulates spermatogenesis and suppresses secretion of LH by acting on hypothalamus and anterior pituitary.
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