Applied Computational Genomics - 05 - Sequence Mapping and Alignment: Methods and Considerations.

From Aaron Quinlan's course on Applied Computational Genomics at the University of Utah (https://github.com/quinlan-lab/applie...). This lecture covers how DNA sequences are mapped and aligned to reference genomes. The lecture introduces core methods such as hash-based mapping strategies, mapping qualities, and the Smith-Waterman dynamic programming algorithm.