File Formats #7: VCF

In this video, I explain the VCF file format — a standard for storing sequence variation information such as single base substitutions, insertions, deletions and complex variants. 📄 Learn More 🔗 Format → https://samtools.github.io/hts-specs/VCFv4.2.pdf 💾 Reference Databases 🔗 Ensembl→ https://asia.ensembl.org/index.html 🔗 Ensembl Genomes → https://ensemblgenomes.org/ 🔗 dbSNP → https://www.ncbi.nlm.nih.gov/snp/ 🔗 ClinVar → https://www.ncbi.nlm.nih.gov/clinvar/ 🧬 Infectious Disease Study 🔗 Research article → https://www.nature.com/articles/s41467-025-56050-2 💻 Variant Calling Tools 🔗 DeepVariant→ https://github.com/google/deepvariant 🔗 GATK → https://github.com/broadinstitute/gatk 🔗 Freebayes → https://github.com/freebayes/freebayes 🔗 Mutect2 → Implemented in GATK package 📺 More Genomics & Bioinformatics Videos 👉 Subscribe for tutorials, data analysis guides, and sequencing deep dives!