Homology Modeling

This video shows how to generate a 3D structural model directly from sequence using the MOE Homology Modeler. 0:25 Loading a sequence 0:47 Searching for templates 2:34 Analyzing templates using the Protein Similarity Monitor 3:11 Analyzing templates using the Sequence Editor Dendrogram 3:52 Realigning the remaining templates for optimum alignment 4:47 Running the Homology Modeler 8:03 Assessing the quality of the structural model using the Protein Geometry application 9:34 Assessing different loop conformations of the intermediate models __________________________________________________________________________________________________ Subscribe to our YouTube channel for updates: https://bit.ly/3ICXK0W Visit CCG at https://www.chemcomp.com/ Listen to our podcast: https://bit.ly/3WQGPKY Follow us on LinkedIn: https://www.linkedin.com/company/chemical-computing-group/ X: https://twitter.com/CCG_MOE/