Rosetta and PyRosetta use “Movers” to manipulate a protein/pose of interest by making modifications to reach a design objective, and most established Rosetta protocols are wrapped as Movers. This video shares commonly used movers and how they work, particularly using RosettaScripts.
Protein Modeling and Design with PyRosetta and Machine Learning
https://www.youtube.com/playlist?list=PLFavr8uo6kSqDB1cbXUDFZSooNk537teC
Video from the Rosetta Commons RaMP Bootcamp (July 2023)
Instructor: Deniz Akpinaroglu (UCSF)
https://docs.rosettacommons.org/docs/latest/scripting_documentation/RosettaScripts/Movers/Movers-RosettaScripts
Credits:
Instructor: Deniz Akpinaroglu (UCSF)
RaMP Director and Rosetta Commons Director: Jeffrey Gray (JHU)
RaMP Program Administrator:Camille Mathis (JHU)
Rosetta Commons Instructional Designer: Ashley Vater (UC Davis)
Video Production: Elizabeth Bonilla (JHU)
Funding: Rosetta Commons, National Science Foundation, and Johns Hopkins University
00:00 - Start
00:32 - The Mover class
03:06 - Alternative ways for initializing movers
04:02 - Lab
