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Sampling and Building Loops with the Loop Modeler

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Oct 17, 2025
4:47

This video shows how to sample and build loop conformations. The Loop and Linker Modeler can be used to sample loops for homology models, build missing loops from X-ray structures, or generate linker units for fusion proteins. 0:47 Identifying the missing loop 1:34 Running the Loop Modeler 2:53 Browsing the backbone conformation of loop candidates 3:14 Building sidechains and repacking the environment 3:56 Browsing the final loop structures __________________________________________________________________________________________________ Subscribe to our YouTube channel for updates: https://bit.ly/3ICXK0W Visit CCG at https://www.chemcomp.com/ Listen to our podcast: https://bit.ly/3WQGPKY Follow us on LinkedIn: https://www.linkedin.com/company/chemical-computing-group/ X: https://twitter.com/CCG_MOE/

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Sampling and Building Loops with the Loop Modeler | NatokHD